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Au-catalyzed cyclization of monoallylic diols

Aaron Aponick1, Chuan-Ying Li, Berenger Biannic

  • 1Department of Chemistry, University of Florida, Gainesville, Florida 32611, USA. aponick@chem.ufl.edu

Organic Letters
|January 26, 2008
PubMed
Summary

A new gold-catalyzed cyclization efficiently synthesizes tetrahydropyrans from monoallylic diols. This reaction is fast, works at low temperatures, and shows high diastereoselectivity for cis products.

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