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Refeeding syndrome in cancer patients
1Wright State University School of Medicine, Division of Hematology-Oncology, Dayton, OH, USA. mmarinella@pol.net
International Journal of Clinical Practice
|January 26, 2008
Summary
Refeeding syndrome (RFS) is a dangerous metabolic complication in malnourished patients receiving nutrition. Oncologists must recognize RFS risk factors and symptoms to prevent severe complications.
Area of Science:
- Oncology
- Internal Medicine
- Critical Care Medicine
Background:
- Refeeding syndrome (RFS) is a common complication in acutely ill, malnourished patients.
- It occurs when nutritional support, particularly glucose, is initiated.
- RFS involves significant electrolyte imbalances.
Observation:
- The hallmark of RFS is hypophosphatemia.
- Hypokalemia and hypomagnesemia are also frequently observed.
- Patients with cancer are at increased risk for RFS.
Findings:
- Malignancy is a significant risk factor for developing refeeding syndrome.
- The oncologic literature inadequately addresses RFS.
- RFS presents with diverse metabolic, cardiovascular, hematologic, and neurologic issues.
Implications:
- Oncologists must be aware of RFS pathophysiology and risk factors.
- Prompt recognition and management of RFS are crucial.
- Understanding RFS can prevent potentially fatal complications in cancer patients.
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