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Superior sagittal sinus thrombosis.

A Mohamed1, J G McLeod, J Hallinan

  • 1Department of Neurology, Royal Price Alfred Hospital, Camperdown, Sydney.

Clinical and Experimental Neurology
|January 1, 1991
PubMed
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Superior sagittal sinus thrombosis (SSST) is a rare condition. Early diagnosis and management of raised intracranial pressure are crucial for favorable outcomes in SSST patients.

Area of Science:

  • Neurology
  • Vascular Neurology
  • Radiology

Background:

  • Superior sagittal sinus thrombosis (SSST) is a rare but serious condition affecting cerebral venous drainage.
  • Diagnosis and management of SSST can be challenging, with varied clinical presentations and underlying causes.

Purpose of the Study:

  • To review cases of SSST diagnosed at a major hospital over a decade.
  • To identify diagnostic features, clinical manifestations, potential causes, and therapeutic considerations for SSST.

Main Methods:

  • Retrospective review of seven SSST cases diagnosed between 1979 and 1989.
  • Diagnostic confirmation through angiography, CT scan, or autopsy.
  • Analysis of patient demographics, clinical symptoms, neurological signs, and identified risk factors.

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Main Results:

  • The average age of affected patients was 33 years, with a higher prevalence in females (5/7).
  • The 'empty delta' sign on CT scan was a specific diagnostic finding in 4 cases.
  • Common symptoms included headache, convulsions, and hemiparesis; raised intracranial pressure preceded focal deficits in 5 patients.
  • Identified causes included primary thrombocythaemia, homocystinuria, post-angiographic arteriovenous malformation, and oral contraceptives.

Conclusions:

  • Prompt recognition and management of elevated intracranial pressure are vital in SSST.
  • While the role of anticoagulation is debated, early use may be considered in the absence of hemorrhage.
  • Further research is needed to establish optimal therapeutic strategies for SSST.