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In vitro Functional Characterization of Mouse Colorectal Afferent Endings
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Comparing different methods of activating the variable stiffness function of a pediatric variable stiffness

Yu-Hsi Hsieh1, An-Liang Zhou, Hwai-Jeng Lin

  • 1Department of Medicine, Buddhist Dalin Tzu Chi General Hospital, Chia-Yi, Taiwan.

Journal of the Chinese Medical Association : JCMA
|January 26, 2008
PubMed
Summary

Activating variable stiffness colonoscopes, especially on an as-needed basis for females, reduced the need for abdominal pressure during colonoscopy. This method did not significantly alter completion rates or intubation times.

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Area of Science:

  • Gastroenterology
  • Medical Devices
  • Endoscopy

Background:

  • Variable stiffness colonoscopes aim to improve procedural outcomes.
  • Previous studies yielded mixed results, potentially due to varied activation methods.
  • This study investigates optimal activation strategies for pediatric variable stiffness colonoscopes.

Purpose of the Study:

  • To compare the efficacy of three variable stiffness activation methods: no activation, regular activation, and as-needed activation.
  • To evaluate the impact of these methods on colonoscopy completion rates, cecal intubation time, and the use of adjunct measures.
  • To determine the most efficient activation strategy for variable stiffness colonoscopes.

Main Methods:

  • A randomized trial involving 250 asymptomatic patients undergoing colonoscopy with a pediatric variable stiffness colonoscope.
  • Patients were assigned to one of three groups: no activation, regular activation, or as-needed activation.
  • Outcomes assessed included completion rate, cecal intubation time, and use of abdominal pressure, with subgroup analysis by gender.

Main Results:

  • No significant differences in overall completion rates or cecal intubation times were observed across the three groups.
  • Activation of the variable stiffness function, both regularly and as-needed, was associated with a reduced need for abdominal pressure.
  • In female patients, as-needed activation was the only setting that showed a significant benefit.
  • In male patients, as-needed activation was associated with a longer cecal intubation time.

Conclusions:

  • Variable stiffness colonoscope activation methods did not significantly impact completion rates or cecal intubation times.
  • Activating the variable stiffness function generally decreased the requirement for abdominal pressure.
  • As-needed activation of the variable stiffness function proved beneficial specifically for female patients.