Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Juvenile parkinsonism. 18 cases].

J L Ferreiro1, M I Pugliese, A E Caride

  • 1División Neurología, Hospital de Clínicas José de San Martín, Facultad de Medicina, Universidad de Buenos Aires, Argentina.

Medicina
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neurohormonal activation induces intracellular iron deficiency and mitochondrial dysfunction in cardiac cells.

Cell & bioscience·2021
Same author

Rationale and study design of the RESERVOIR trial: a randomized trial comparing reservoir-based polymer-free amphilimus-eluting stents versus everolimus-eluting stents with durable polymer in patients with diabetes mellitus.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2014
Same author

Antiplatelet therapy: new pharmacological agents and changing paradigms.

Journal of thrombosis and haemostasis : JTH·2013
Same author

Clinical reasoning: a 35-year-old man with a right hemiplegia and a cerebral mass.

Neurology·2009
Same author

[Osteoarticular infections caused by Streptococcus agalactiae. Report of 4 cases].

Enfermedades infecciosas y microbiologia clinica·1995
Same author

Case report 866. Pseudotumor of the muscle associated with necrotizing vasculitis of medium- and small-sized arteries and chronic myositis.

Skeletal radiology·1994

Juvenile Parkinsonism, affecting individuals under 40, shows slower L-Dopa therapy impairment. This impairment appears linked to illness duration rather than treatment length in young-onset Parkinson

Area of Science:

  • Neurology
  • Movement Disorders
  • Genetics

Context:

  • Juvenile Parkinsonism (JP) is defined by symptom onset before age 40.
  • This study focuses on 18 JP patients aged 15-34 with 9-17 years of follow-up.

Purpose:

  • To elucidate the essential features of juvenile parkinsonism.
  • To analyze the clinical, evolutive, and therapeutic aspects of JP.
  • To compare JP progression with literature data.

Summary:

  • Patients with juvenile Parkinsonism exhibit a slower development of L-Dopa therapy impairment compared to presenile forms.
  • The observed L-Dopa resistance is primarily associated with the duration of the illness, not the length of L-Dopa treatment.

Impact:

Related Experiment Videos

  • Provides crucial insights into the long-term management of juvenile Parkinsonism.
  • Informs therapeutic strategies by highlighting the relationship between disease duration and L-Dopa efficacy.
  • Contributes to a better understanding of Parkinson's disease heterogeneity.