[Personality characteristics as a prognostic factor in using antidepressive drugs in endogenous depression]

The study aimed to test usefulness of personality patterns for prediction of efficacy of antidepressant drugs in patients with endogenous depression. No association between a positive response to treatment and such personality traits as neuroticism, extraversion, nervous system reactivity or MMPI clinical scales profile was demonstrated. A positive response to the pharmacological treatment was significantly more frequently observed in persons characterized by a capability to control expression of mental symptoms (subscale Cn in MMPI). A lack of response to treatment was more frequently observed in persons demonstrating high scores in lie scales of MMPI and MPI and characterized by higher score in Re (responsibility) subscale of MMPI.