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Published on: November 7, 2018
[Season and age related structure of acute intestinal infections morbidity in the Russian Federation]
Insights
This study investigated the causes of acute intestinal infections (AII) in Russia, finding viral agents like rotaviruses and noroviruses are common in children and adults. Etiological structures and seasonal trends of AII were characterized.
Area of Science:
- Infectious Diseases
- Virology
- Epidemiology
Context:
- Acute intestinal infections (AII) pose a significant public health challenge globally.
- Understanding the etiological landscape of AII is crucial for effective prevention and treatment strategies.
- Previous research has indicated variations in AII causes based on age and geographic location.
Purpose:
- To investigate the seasonal and age-specific etiological structure of acute intestinal infections (AII) within the Russian Federation.
- To identify the prevalence of various viral and bacterial pathogens causing AII across different age groups.
- To analyze temporal trends in AII morbidity.
Summary:
- A study of 7388 AII inpatients (aged 1 day to 90 years) across seven Russian cities from 2001-2006 utilized PCR diagnostics.
- Rotaviruses (RVA) and noroviruses were the most frequent viral agents in children (29.5% and 11%).
- Adults most commonly presented with Salmonella (9.3%), noroviruses (8.4%), RVA (7.8%), and Shigella with EIEC (7.0%).
Impact:
- Viral agents are identified as primary causative agents of AII across all age demographics.
- The findings highlight distinct age-related and seasonal patterns in AII etiology.
- This research provides valuable data for public health interventions and disease surveillance in Russia.
Aim:
To study seasonal and age features of etiological structure of acute intestinal infections (AII) in the territory of the RF.
Material And Methods:
A total of 7388 AII inpatients aged from 1 day to 90 years from 7 cities (Moscow, St-Petersburg, Nizhniy Novgorod, Chelyabinsk, Tyumen, Makhachkala and Khabarovsk) of the RF participated in a trial conducted from December 2001 to September 2006 The patients were examined with diagnostic tests based on polymerase chain reaction (PCR) for detection of rotaviruses of group A (RVA), noroviruses, astroviruses, adenoviruses, salmonella, termophilic campilobacteria, shigella and enteroinvasive Escherichia coli (EIEC).
Results:
The above agents were detected in 72% children and 52% adults. In children RVA and noroviruses occurred most frequently (29.5% and 11%, respectively). The adults carried most often salmonella (9.3%), noroviruses (8.4%), RVA (7.8%) and Schigella in combination with EIEC (7.0%).
Conclusion:
Viral agents are essential or prevailing causative agents of AII at different ages. Seasonal and age-related trends of AII morbidity are characterized.
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