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Updated: Jul 8, 2026

Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
[Characteristics of respiratory disorders in acute leukemia]
Aim:
To characterize respiratory disorders and microflora in patients with acute leukemia (AL).
Material And Methods:
Examination of the respiratory organs was made in 72 patients admitted to Hematological Center of Armenia (HCA) in 2005. Also, a retrospective analysis of the records on 126 AL patients treated in HCA during 2002-2004 was made.
Results:
Lesions of the lungs and mediastinum were detected in 61 (30.8%) patients. Infectious complications were found in 45 (73.8%) patients, of them 30 (48.3%) patients had pneumonia. Interstitial pneumonia, chronic bronchitis, exudative pleurisy, pulmonary tuberculosis, fungal affection of the lungs were diagnosed in 5, 5, 10, 6 and 4 patients, respectively. Bacterial flora caused pneumonia in 30 patients. Gram positive and negative flora was found in 9 out of 24 cases. In 5 patients the flora was mixed. The policy of the antibacterial treatment was proposed. Roentgenological semiography in different pulmonary affections has characteristic features. Leukemoid infiltration of the lungs occurred in 6 AL patients. Blast pleurisy was found in 6 patients.
Conclusion:
The policy of correction of microbial spectrum in AL patients using optimal schemes of antibacterial therapy is proposed.
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