Related Experiment Video
Updated: Jul 8, 2026

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
Published on: May 16, 2021
A new model for academics based drug discovery.
1Laboratory for Drug Discovery in Neurodegeneration, Harvard Center for Neurodegeneration and Repair, 65 Landsdowne Street, Cambridge, MA 02139, USA. rstein@rics.bwh.harvard.edu
New drug discovery models are needed to address rare diseases neglected by pharmaceutical companies. This presentation outlines a novel approach for developing treatments for neurodegenerative diseases.
Area of Science:
- Neuroscience
- Pharmacology
- Drug Discovery
Background:
- Drug discovery is a complex, expensive process traditionally dominated by the pharmaceutical industry.
- Industry focus on profitable markets often leaves rare and neurodegenerative diseases underserved.
- There is a societal need for innovative models to drive research in neglected disease areas.
Purpose of the Study:
- To present a novel model for facilitating drug discovery in neglected disease areas.
- To specifically address the development of treatments for neurodegenerative diseases.
Main Methods:
- The presentation will describe a specific model designed for drug discovery.
- This model aims to overcome the financial barriers faced by traditional pharmaceutical research.
Main Results:
- The model has been established to find treatments for neurodegenerative diseases.
- Details on the model's specific mechanisms and successes will be discussed.
Conclusions:
- The established model offers a viable alternative for pursuing treatments for neurodegenerative conditions.
- This approach encourages drug discovery in areas neglected by the pharmaceutical industry due to financial constraints.
Related Concept Videos
Drug Discovery: Overview
Structure-Activity Relationships and Drug Design
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence its...
Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions
Pharmacodynamic Models: Emax Drug–Concentration Effect Model
Pharmacogenomics: Identification of New Drug Targets
Pharmacodynamic Models: Overview
