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Related Concept Videos

What is Metabolism?00:52

What is Metabolism?

Overview
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Overview of Metabolism01:40

Overview of Metabolism

Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Introduction to Metabolism01:30

Introduction to Metabolism

Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
Regulation of Metabolism01:19

Regulation of Metabolism

Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...

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Updated: Jul 8, 2026

A Strategy for Sensitive, Large Scale Quantitative Metabolomics
14:18

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

Published on: May 27, 2014

Metabolomics.

V S Gomase1, S S Changbhale, S A Patil

  • 1Dept. of Bioinformatics, Dr. D.Y. Patil Institute for Biotechnology and Bioinformatics, Padmashree Dr. D.Y. Patil University, Plot No-50, Sector-15, CBD Belapur, Navi Mumbai, 400614, India. virusgene1@yahoo.co.in

Current Drug Metabolism
|January 29, 2008
PubMed
Summary
This summary is machine-generated.

Metabolomics analyzes small molecules in biological samples to provide a snapshot of cell physiology. This field aids in understanding gene function and building complex biological models for systems biology applications.

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Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS)

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Last Updated: Jul 8, 2026

A Strategy for Sensitive, Large Scale Quantitative Metabolomics
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Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
11:02

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

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Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS)
07:34

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS)

Published on: March 14, 2013

Area of Science:

  • Biochemistry
  • Systems Biology
  • Molecular Biology

Background:

  • Metabolomics involves the simultaneous analysis of numerous low-molecular-weight metabolites.
  • It aims to catalog and quantify small molecules in biological fluids under various conditions.
  • Metabolic profiling offers an instantaneous view of cellular physiology.

Purpose of the Study:

  • To strengthen the role of metabolomics in understanding in vivo gene product function.
  • To advance biochemical analysis and regulatory network studies.
  • To contribute to the mathematical description and simulation of cellular processes within systems biology.

Main Methods:

  • Simultaneous analysis of multiple metabolites.
  • Cataloging and quantification of small molecules in biological fluids.
  • Integration with genomics and proteomics data.

Main Results:

  • Provides an instantaneous snapshot of cell physiology.
  • Enhances understanding of in vivo gene product function.
  • Facilitates the construction of designer organisms for biotransformation and fermentation.

Conclusions:

  • Metabolomics is crucial for a detailed understanding of biological systems.
  • It enables the connection of multi-omics data for a holistic approach.
  • Applications include creating designer organisms and optimizing bioprocesses.