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05:57
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Published on: April 26, 2024
Recent patents on bacterial proteins as potential anticancer agents
Arsenio M Fialho1, Ananda M Chakrabarty
1Instituto for Biotechnology and BioEngineering (IBB), Center for Biological and Chemical Engineering, Instituto Superior Tecnico, 1049-001 Lisbon, Portugal.
Recent Patents on Anti-Cancer Drug Discovery
|January 29, 2008
Summary
This review explores patents on bacterial proteins for cancer treatment. These proteins show anticancer, antiviral, and antiparasitic potential, offering new therapeutic avenues.
Area of Science:
- Biotechnology
- Oncology
- Microbiology
Background:
- Traditional anticancer agents include small molecules and monoclonal antibodies.
- Emerging research investigates bacterial pathogens for cancer regression.
- Patents exist for engineered bacteria and bacterial components as therapeutic agents.
Purpose of the Study:
- To review patents claiming bacterial proteins as anticancer agents.
- To highlight bacterial proteins with broad therapeutic applications beyond cancer.
- To discuss patents involving CpG-rich DNA for cancer therapy.
Main Methods:
- Literature review of patents related to bacterial proteins and cancer treatment.
- Analysis of patents detailing bacterial protein characterization and application.
- Examination of patents covering CpG-rich DNA as therapeutic agents.
Main Results:
- Identified patents for specific bacterial proteins with demonstrated anticancer activity.
- Highlighted two bacterial proteins exhibiting anticancer, antiviral, and antiparasitic effects.
- Noted patents covering the use of CpG-rich DNA, including bacterial DNA, for cancer treatment.
Conclusions:
- Bacterial proteins represent a promising class of agents for cancer therapy.
- Certain bacterial proteins possess multifaceted therapeutic potential against cancer, viral, and parasitic diseases.
- Patented bacterial components and DNA offer novel strategies for oncological and infectious disease treatment.
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