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Recent patents on bacterial proteins as potential anticancer agents

Arsenio M Fialho1, Ananda M Chakrabarty

  • 1Instituto for Biotechnology and BioEngineering (IBB), Center for Biological and Chemical Engineering, Instituto Superior Tecnico, 1049-001 Lisbon, Portugal.

Recent Patents on Anti-Cancer Drug Discovery
|January 29, 2008
PubMed

Insights

This review explores patents on bacterial proteins for cancer treatment. These proteins show anticancer, antiviral, and antiparasitic potential, offering new therapeutic avenues.

Area of Science:

  • Biotechnology
  • Oncology
  • Microbiology

Background:

  • Traditional anticancer agents include small molecules and monoclonal antibodies.
  • Emerging research investigates bacterial pathogens for cancer regression.
  • Patents exist for engineered bacteria and bacterial components as therapeutic agents.

Purpose of the Study:

  • To review patents claiming bacterial proteins as anticancer agents.
  • To highlight bacterial proteins with broad therapeutic applications beyond cancer.
  • To discuss patents involving CpG-rich DNA for cancer therapy.

Main Methods:

  • Literature review of patents related to bacterial proteins and cancer treatment.
  • Analysis of patents detailing bacterial protein characterization and application.
  • Examination of patents covering CpG-rich DNA as therapeutic agents.

Main Results:

  • Identified patents for specific bacterial proteins with demonstrated anticancer activity.
  • Highlighted two bacterial proteins exhibiting anticancer, antiviral, and antiparasitic effects.
  • Noted patents covering the use of CpG-rich DNA, including bacterial DNA, for cancer treatment.

Conclusions:

  • Bacterial proteins represent a promising class of agents for cancer therapy.
  • Certain bacterial proteins possess multifaceted therapeutic potential against cancer, viral, and parasitic diseases.
  • Patented bacterial components and DNA offer novel strategies for oncological and infectious disease treatment.

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