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Recent patents on proteases and kinases as anti-infective agents: a review

Surya N Vangapandu1, Ritu Aneja, Ramesh Chandra

  • 1Laboratory for Drug Discovery and Research, Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA. svangap@emory.edu

Recent Patents on Anti-Infective Drug Discovery
|January 29, 2008
PubMed

Insights

New drug development is crucial to combat evolving infectious diseases and antibiotic resistance. This review highlights key patents for protease and kinase inhibitors, advancing new treatments from the lab to the clinic.

Area of Science:

  • Microbiology
  • Pharmacology
  • Drug Discovery

Background:

  • Infectious diseases pose a persistent global health challenge due to evolving pathogens and increasing antibiotic resistance.
  • The emergence of new pathogenic species and resistance to existing antibiotics necessitates novel therapeutic strategies.
  • Patents represent crucial steps in the drug development pipeline, signaling innovation in combating infectious agents.

Purpose of the Study:

  • To review select patents licensed for drug development targeting infectious diseases.
  • To highlight innovations in protease and kinase inhibitors for therapeutic applications.
  • To inform the public about the status of new anti-infective technologies in clinical development.

Main Methods:

  • Selective review of patents related to protease and kinase inhibitors for infectious disease treatment.
  • Analysis of patent licensing status for drug development.
  • Literature and patent database search for relevant innovations.

Main Results:

  • Several key patents for protease and kinase inhibitors have been identified and licensed for drug development.
  • These patented technologies show promise in addressing challenges posed by emerging and resistant pathogens.
  • The review provides insights into the current landscape of anti-infective drug development pipelines.

Conclusions:

  • Protease and kinase inhibitors are critical targets for developing new anti-infective drugs.
  • Patent-backed innovations are vital for advancing novel treatments against infectious diseases.
  • Continued research and development are essential to translate these technologies into effective clinical therapies.

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