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Very high and increasing incidence of type 1 diabetes mellitus in Newfoundland and Labrador, Canada

L A Newhook1, M Grant, S Sloka

  • 1Department of Pediatrics, Memorial University, St. John's, Newfoundland and Labrador, Canada. lnewhook@mun.ca

Pediatric Diabetes
|January 29, 2008
PubMed

Insights

Newfoundland and Labrador has one of the world's highest rates of type 1 diabetes mellitus (T1DM) in children. This study found the incidence of T1DM is increasing in children aged 0-14 years.

Area of Science:

  • Pediatric Endocrinology
  • Epidemiology
  • Public Health

Background:

  • Type 1 diabetes mellitus (T1DM) is a significant global health concern, particularly in pediatric populations.
  • Understanding regional incidence patterns is crucial for resource allocation and public health interventions.

Purpose of the Study:

  • To determine the incidence of T1DM in children aged 0-14 years in Newfoundland and Labrador (NL).
  • To analyze trends and demographic variations in T1DM incidence within this population.

Main Methods:

  • A prospective and retrospective cohort study was conducted from 1987 to 2005.
  • Case ascertainment utilized multiple sources, with verification through the capture-recapture technique.

Main Results:

  • A total of 732 children aged 0-14 years were diagnosed with T1DM during the study period.
  • The overall incidence was 35.08 per 100,000 children, with a significant linear increase of 0.78 per 100,000 annually.
  • Boys aged 0-4 years showed a higher incidence (31.61 per 100,000) compared to girls (19.05 per 100,000).

Conclusions:

  • Newfoundland and Labrador exhibits one of the highest T1DM incidences globally.
  • The rising trend in T1DM incidence over the 19-year study period highlights an ongoing public health challenge.
Abstract

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