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Venous Thrombosis I: Introduction

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...

Transient Ischemic Attack l: Introduction

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...

Venous Thrombosis III: Interprofessional Care

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

Ischemic Stroke l: Introduction

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Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.

Pulmonary Embolism I: Introduction

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...

Pulmonary Embolism I: Introduction

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...

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Related Experiment Video

Updated: Jul 7, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

[Stent thrombosis].

D Martí Sánchez¹, N Dedieu, L Salido Tahoces

¹Servicio de Cardiología, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Madrid, Spain. docalcala@hotmail.com

Revista Clinica Espanola

|January 29, 2008

Summary

This summary is machine-generated.

Stent thrombosis (ST) is a rare but serious complication after coronary stent placement. Prematurely stopping antiplatelet therapy significantly increases the risk of ST, especially with drug-eluting stents.

Related Experiment Videos

Last Updated: Jul 7, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

Area of Science:

Cardiology
Interventional Cardiology
Biomedical Engineering

Context:

Stent thrombosis (ST) is a rare but life-threatening complication following coronary endoprosthesis implantation.
Clinical trials indicate no significant difference in early and late thrombosis rates between bare-metal stents (BMS) and drug-eluting stents (DES).
Very late stent thrombosis, occurring over a year post-implantation, is more frequently associated with DES.

Purpose:

To review the pathogenesis and risk factors associated with stent thrombosis.
To highlight the critical role of antiplatelet therapy in preventing ST.
To outline current recommendations for antiplatelet therapy duration after BMS and DES implantation.

Summary:

ST involves patient, stent, lesion, and procedural factors.
The primary risk factor for ST is the premature cessation of antiplatelet therapy.
Current guidelines recommend aspirin and a thienopyridine for at least one month (BMS) or 12 months (DES), followed by indefinite single antiplatelet therapy.

Impact:

Understanding ST pathogenesis and risk factors is crucial for improving patient outcomes.
Adherence to antiplatelet therapy protocols is essential for minimizing ST incidence.
This review provides a concise overview of ST, aiding clinicians in patient management and risk stratification.