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Updated: Jul 7, 2026

Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture

Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture

Published on: April 8, 2016

Cutaneous Hodgkin's disease.

Camille E Introcaso¹, Jonathan Kantor, David L Porter

¹Department of Dermatology, the University of Pennsylvania, Philadelphia, USA.

Journal of the American Academy of Dermatology

|January 29, 2008

Summary

This summary is machine-generated.

Cutaneous Hodgkin

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Last Updated: Jul 7, 2026

Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture

Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture

Published on: April 8, 2016

Area of Science:

Oncology
Dermatology

Background:

Cutaneous Hodgkin's disease is a rare, late-stage manifestation of Hodgkin's lymphoma.
Improved treatments like chemotherapy, radiation, and stem cell transplantation have decreased its incidence.

Observation:

A case of a man with recurrent Hodgkin's lymphoma who developed specific cutaneous Hodgkin's lymphoma 6 months post-allogeneic stem cell transplantation.
The relapse presented as skin dissemination with erythematous papules and ulcerated nodules, despite minimal systemic disease.

Findings:

The patient's cutaneous lesions were typical in morphology and distribution for specific cutaneous Hodgkin's disease.
This case highlights cutaneous dissemination as a potential complication after stem cell transplantation for Hodgkin's lymphoma.

Implications:

Emphasizes the importance of early diagnosis of cutaneous Hodgkin's disease for effective treatment.
Suggests vigilant skin monitoring in patients post-stem cell transplantation for hematologic malignancies.