Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Reconstruction of Signal using Interpolation01:10

Reconstruction of Signal using Interpolation

Signal processing techniques are essential for accurately converting continuous signals to digital formats and vice versa. When a continuous signal is sampled with a period T, the resulting sampled signal exhibits replicas of the original spectrum in the frequency domain, spaced at intervals equal to the sampling frequency. To handle this sampled signal, a zero-order hold method can be applied, which creates a piecewise constant signal by retaining each sample's value until the next sampling...
Deconvolution01:20

Deconvolution

Deconvolution, also known as inverse filtering, is the process of extracting the impulse response from known input and output signals. This technique is vital in scenarios where the system's characteristics are unknown, and they must be inferred from the observable signals.
Deconvolution involves several mathematical techniques to derive the impulse response. One common approach is polynomial division. In this method, the input and output sequences are treated as coefficients of...
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Residuals and Least-Squares Property01:11

Residuals and Least-Squares Property

The vertical distance between the actual value of y and the estimated value of y. In other words, it measures the vertical distance between the actual data point and the predicted point on the line
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adaptive changes in early and late blind: a fMRI study of Braille reading.

Journal of neurophysiologyยท2002
Same author

Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study.

Biological psychiatryยท2001
Same author

Direct comparison of prefrontal cortex regions engaged by working and long-term memory tasks.

NeuroImageยท2001
Same author

The emotional modulation of cognitive processing: an fMRI study.

Journal of cognitive neuroscienceยท2001
Same author

Human brain activity time-locked to perceptual event boundaries.

Nature neuroscienceยท2001
Same author

Dissociating state and item components of recognition memory using fMRI.

NeuroImageยท2001

Related Experiment Video

Updated: Jul 7, 2026

Three-Dimensional Mapping of the Rotation of Interactive Virtual Objects with Eye-Tracking Data
06:36

Three-Dimensional Mapping of the Rotation of Interactive Virtual Objects with Eye-Tracking Data

Published on: October 18, 2024

Iterative reconstruction-reprojection and the expectation-maximization algorithm.

J M Ollinger1

  • 1Hospital of the Univ. of Pennsylvania, Philadelphia, PA.

IEEE Transactions on Medical Imaging
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

The iterative reconstruction-reprojection (IRR) algorithm estimates missing computed tomography data. This expectation-maximization method works well with noisy datasets, offering improved accuracy.

More Related Videos

Single Particle Electron Microscopy Reconstruction of the Exosome Complex Using the Random Conical Tilt Method
12:10

Single Particle Electron Microscopy Reconstruction of the Exosome Complex Using the Random Conical Tilt Method

Published on: March 28, 2011

Related Experiment Videos

Last Updated: Jul 7, 2026

Three-Dimensional Mapping of the Rotation of Interactive Virtual Objects with Eye-Tracking Data
06:36

Three-Dimensional Mapping of the Rotation of Interactive Virtual Objects with Eye-Tracking Data

Published on: October 18, 2024

Single Particle Electron Microscopy Reconstruction of the Exosome Complex Using the Random Conical Tilt Method
12:10

Single Particle Electron Microscopy Reconstruction of the Exosome Complex Using the Random Conical Tilt Method

Published on: March 28, 2011

Area of Science:

  • Medical Imaging
  • Computational Imaging
  • Image Reconstruction

Background:

  • Computed tomography (CT) requires complete projection data for accurate image reconstruction.
  • Missing or noisy projection data can significantly degrade image quality and diagnostic utility.
  • Existing algorithms may struggle with inconsistent or incomplete datasets.

Purpose of the Study:

  • To introduce and validate the iterative reconstruction-reprojection (IRR) algorithm for estimating missing CT projections.
  • To demonstrate the suitability of IRR for handling noisy projection data.
  • To provide theoretical and simulation-based evidence for IRR's performance.

Main Methods:

  • The iterative reconstruction-reprojection (IRR) algorithm was derived from an expectation-maximization (EM) framework.
  • The algorithm loosens the strict consistency constraint on projection data.
  • Convergence and monotonicity properties of the IRR algorithm were mathematically proven.

Main Results:

  • The IRR algorithm demonstrated effectiveness in estimating missing projections in computed tomography.
  • The method showed robustness and suitability for use with noisy projection data.
  • Theoretical proofs confirmed the algorithm's convergence to a stationary point and monotonic sequence of iterates.

Conclusions:

  • The iterative reconstruction-reprojection (IRR) algorithm offers a robust solution for incomplete and noisy CT projection data.
  • IRR provides a valuable tool for improving image reconstruction quality in challenging CT acquisition scenarios.
  • The algorithm's mathematical properties support its reliability in practical applications.