Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chromosome structure and eukaryotic gene organization.

D Kitsberg1, S Selig, H Cedar

  • 1Department of Cellular Biochemistry, Hebrew University, Hadassah Medical School, Jerusalem, Israel.

Current Opinion in Genetics & Development
|December 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The drinking water crises of Flint and Havelock North: a failure of public health risk management.

Journal of water and health·2022
Same author

A case for diagnosis.

Clinical and experimental dermatology·2015
Same author

Oxygen (O2) kinetics during early recovery from peak exercise in patients with Type 2 diabetes.

Diabetic medicine : a journal of the British Diabetic Association·2011
Same author

The effect of acute exercise on undercarboxylated osteocalcin in obese men.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2010
Same author

Inflammation, hepatic enzymes and resistance training in individuals with metabolic risk factors.

Diabetic medicine : a journal of the British Diabetic Association·2009
Same author

Ammonia, cyclohexane, nitrogen and water adsorption capacities of an activated carbon impregnated with increasing amounts of ZnCl(2), and designed to chemisorb gaseous NH(3) from an air stream.

Journal of colloid and interface science·2008

Eukaryotic DNA is organized into distinct chromosomal bands and chromatin loops. These functional domains have boundary elements and are regulated during development.

Area of Science:

  • Molecular Biology
  • Genetics
  • Cell Biology

Background:

  • Eukaryotic nuclear DNA is highly compacted.
  • DNA organization is crucial for nuclear function.
  • Chromosomal structures play a role in genome regulation.

Purpose of the Study:

  • To describe the organization of eukaryotic nuclear DNA.
  • To highlight the functional significance of chromatin loops and boundary elements.
  • To explain the developmental regulation of these structures.

Main Methods:

  • Analysis of DNA organization in eukaryotic nuclei.
  • Characterization of chromosomal bands and their properties.
  • Identification of chromatin loops and their boundary elements.

Related Experiment Videos

Main Results:

  • Eukaryotic DNA is organized into distinct regional units and chromosomal bands.
  • Chromosomal bands exhibit characteristic structures and replication times.
  • Chromatin loops serve as functional domains with discrete boundary elements.
  • These domains are subject to developmental regulation.

Conclusions:

  • The highly compacted eukaryotic DNA is organized into well-defined structures.
  • Chromatin loops and their boundary elements represent key functional domains.
  • Developmental regulation impacts the organization and function of these DNA domains.