Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Modifiability of pattern generation.

E Marder1

  • 1Biology Department, Brandeis University, Waltham, Massachusetts 02254.

Current Opinion in Neurobiology
|December 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oscillating Networks: Control of Burst Duration by Electrically Coupled Neurons.

Neural computation·2019
Same author

Central pattern generators and the control of rhythmic movements.

Current biology : CB·2001
Same author

Prevalence of autism in early 1970s may have been underestimated.

BMJ (Clinical research ed.)·2001
Same author

GABA enhances transmission at an excitatory glutamatergic synapse.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2001
Same author

Global structure, robustness, and modulation of neuronal models.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2001
Same author

Modulators with convergent cellular actions elicit distinct circuit outputs.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2001
Same journal

Cichlid fish as a model for understanding social dysfunction.

Current opinion in neurobiology·2026
Same journal

On aims and methods in field neuroethology: Investigating neural mechanisms of behavior in semi-natural and natural contexts.

Current opinion in neurobiology·2026
Same journal

Neurobiological interfaces connecting environmental change to monarch butterfly migration.

Current opinion in neurobiology·2026
Same journal

Learning how to experience the world: From circuits to cell types to genes.

Current opinion in neurobiology·2026
Same journal

Editorial overview for neurobiology of disease 2026.

Current opinion in neurobiology·2026
Same journal

Optical voltage imaging: ready to spark systems neuroscience.

Current opinion in neurobiology·2026
See all related articles

Animal rhythmic movements rely on neuronal circuits. New research reveals how these circuits adapt to sensory, central, and hormonal signals for flexible behavioral responses.

Area of Science:

  • Neuroscience
  • Animal Behavior
  • Motor Control

Background:

  • Rhythmic movements in animals, such as locomotion and respiration, are fundamental behaviors.
  • These movements are generated by specialized neuronal circuits known as central pattern generators (CPGs).
  • The adaptability of CPGs is crucial for animals to adjust their motor output to changing internal and external conditions.

Purpose of the Study:

  • To explore the cellular mechanisms underlying the flexibility of central pattern generating circuits.
  • To understand how sensory, central, and hormonal inputs modulate CPG function.
  • To elucidate how CPG reorganization enables adaptive behavioral responses.

Main Methods:

  • The study likely involves a combination of electrophysiological recordings, genetic manipulations, and behavioral analyses in model organisms.

Related Experiment Videos

  • Investigating the plasticity of neuronal connections within CPGs.
  • Examining the impact of specific neuromodulators and sensory feedback on CPG output patterns.
  • Main Results:

    • New insights into the cellular and molecular players that mediate CPG plasticity.
    • Demonstration of how different types of inputs dynamically alter CPG network activity.
    • Evidence linking CPG reorganization to specific adaptive behaviors in response to environmental or internal cues.

    Conclusions:

    • Central pattern generating circuits possess significant cellular plasticity.
    • Sensory, central, and hormonal inputs play critical roles in dynamically reconfiguring CPGs.
    • This neural flexibility allows animals to exhibit adaptive rhythmic motor behaviors essential for survival and interaction with their environment.