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Awareness and memory function during paediatric anaesthesia.

J Andrade1, C Deeprose, I Barker

  • 1School of Psychology, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK. j.andrade@plymouth.ac.uk

British Journal of Anaesthesia
|January 29, 2008
PubMed
Summary
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Intraoperative awareness during pediatric anesthesia occurred in 1.1% of children, with no evidence of memory priming. This study highlights a higher incidence in children compared to adults, emphasizing the need for careful anesthetic management.

Area of Science:

  • Anesthesiology
  • Pediatric Surgery
  • Neuroscience

Background:

  • Previous research suggests higher awareness during anesthesia in children than adults.
  • This study is the first large-scale assessment of intraoperative awareness in pediatric anesthesia using the isolated forearm technique.
  • It is also the first large-scale study on memory function during pediatric anesthesia.

Purpose of the Study:

  • To assess the incidence of intraoperative awareness in children undergoing anesthesia.
  • To evaluate memory function (implicit and explicit) during pediatric anesthesia.
  • To investigate behavioral changes associated with anesthesia in children.

Main Methods:

  • 184 children (5-18 years) underwent the modified isolated forearm technique during volatile anesthesia.

Related Experiment Videos

  • Bispectral index monitoring was performed in a subset of patients.
  • Implicit memory was tested via word identification, and explicit memory via structured interview post-anesthesia.

    • Main Results:

    • No child exhibited explicit recall of intraoperative events or implicit memory for presented words.
    • The incidence of intraoperative awareness was 1.1% (2 out of 184 children).
    • One child reported discomfort; neither of the two aware children showed implicit memory or adverse behavioral changes.

    Conclusions:

    • The incidence of intraoperative awareness in children is significantly higher (approx. 8x) than in adults based on postoperative recall.
    • Unlike adults, no evidence of preserved memory priming was found in children during anesthesia.
    • Findings underscore the importance of monitoring and managing awareness during pediatric anesthesia.