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Updated: Jul 7, 2026

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
Published on: June 26, 2020
RecO is essential for DNA damage repair in Deinococcus radiodurans
Guangzhi Xu1, Liangyan Wang, Huan Chen
1Key Laboratory of Chinese Ministry of Agriculture and Zhejiang Province for Nuclear-Agricultural Sciences, Institute of Nuclear-Agricultural Sciences, Zhejiang University, Hangzhou 310029, China.
Abstract:
Here we present direct evidence for the vital role of RecO in Deinococcus radiodurans's radioresistance. A recO null mutant was constructed using a deletion replacement method. The mutant exhibited a growth defect and extreme sensitivity to irradiation with gamma rays and UV light. These results suggest that DNA repair in this organism occurs mainly via the RecF pathway.
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