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Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

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Choroidal sclerosis in localized scleroderma (morphea en plaque).

S Milenkovic¹, L Petrovic, D Risimic

¹Institute of Ophthalmology, University Clinical Center of Serbia, Belgrade, Serbia.

Ophthalmic Research

|January 29, 2008

Summary

This study reports a unique case of plaque morphea (localized scleroderma) with severe ocular complications, including choroidal sclerosis. This highlights the importance of investigating visual changes in morphea patients.

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Area of Science:

Dermatology
Ophthalmology

Background:

Morphea en plaque is a superficial form of localized scleroderma affecting the dermis.
It typically presents without systemic manifestations.

Observation:

A 63-year-old man with plaque morphea on his forearms and feet exhibited taut, thickened skin with telangiectasias.
He presented with decreased vision in his only functional eye.
Autoantibody testing revealed positive antinuclear antibodies (ANA).

Findings:

The patient displayed significant ocular involvement, specifically choroidal sclerosis and a unique fundus appearance.
This presentation is notable as the patient was previously asymptomatic, making the morphea and vision loss highly significant.

Implications:

This case underscores the potential for severe ocular complications in plaque morphea, even in previously healthy individuals.
It emphasizes the need for ophthalmological evaluation in patients with morphea, particularly when visual disturbances are present.
This is the first reported instance of such extensive ocular involvement in plaque morphea.