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Epstein-Barr virus in oral proliferative verrucous leukoplakia and squamous cell carcinoma: A preliminary study

Jose V Bagan1, Yolanda Jiménez, Judith Murillo

  • 1Oral Medicine, Valencia University, Department of Stomatology, University General Hospital, Valencia, Spain. bagan@uv.es

Medicina Oral, Patologia Oral Y Cirugia Bucal
|January 29, 2008
PubMed

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Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...