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Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
[Allergic bronchopulmonary aspergillosis: 3 cases]
Ferda Oner Erkekol1, Sevim Bavbek, Ozlem Göksel
1Division of Allergies, Department of Chest Diseases, Faculty of Medicine, Ankara University, Ankara, Turkey.
Abstract:
Allergic bronchopulmonary aspergillosis (ABPA) occurs in approximately 1-7.6% of patients with asthma. This incidence is low enough not to be considered in the differential diagnosis but also high enough to be an important disease. Since the symptoms and laboratory tests are not specific for ABPA, the diagnosis may be delay for years. However the failure to diagnose and treat ABPA for long term may result in fibrotic lung disease. This article focuses on the clinical and the laboratory aspects, and the management of ABPA in the light of three cases.
Insights
Allergic bronchopulmonary aspergillosis (ABPA) affects 1-7.6% of asthma patients. Early diagnosis and treatment are crucial to prevent long-term lung damage.
Area of Science:
- Pulmonology
- Allergy and Immunology
Background:
- Allergic bronchopulmonary aspergillosis (ABPA) is a lung disease that affects patients with asthma.
- It occurs in 1-7.6% of asthma patients, highlighting its clinical significance.
Observation:
- ABPA symptoms and lab tests are often non-specific, leading to diagnostic delays.
- Delayed diagnosis and treatment can result in irreversible fibrotic lung disease.
Findings:
- This article reviews the clinical and laboratory features of ABPA.
- It also discusses the management strategies for ABPA, illustrated through three case studies.
Implications:
- Highlights the importance of considering ABPA in asthma patients with persistent or worsening symptoms.
- Emphasizes the need for timely diagnosis and appropriate management to prevent severe lung complications.
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