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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Endovascular management of ruptured cerebral mycotic aneurysms
S Dhomne1, C Rao, M Shrivastava
1Department of Radiology, Neuro-interventional Division, King Edward Memorial Hospital, Mumbai, India.
Abstract:
The purpose of this investigation was to evaluate the current endovascular management of cerebral mycotic aneurysms. We report the retrospective evaluation of data of patients with cerebral mycotic aneurysms treated with endovascular approach. Thirteen consecutive patients with cerebral mycotic aneurysms were treated between April 2001 and March 2007. There were seven men and six women with ages ranging from 20 to 52 years (mean age 33 years.). All 13 patients had rheumatic heart disease (RHD) with endocarditis. The aneurysms were located within the distal cerebral circulation (n = 12) or in the circle of Willis (n = 1). All were ruptured aneurysms. Distal aneurysms were treated by parent vessel occlusion. Proximal saccular aneurysms were selectively treated. Endovascular treatment was technically successful in all patients. No patient had a rebleed after embolization during the clinical follow-up. Two patients deteriorated and died after endovascular treatment. Repeat CT scan showed increased mass effect because of earlier intracerebral bleed. The late clinical outcome in the other 11 patients was normal neurological status (n = 8) or permanent disability that was related to the initial stroke (n = 3). Endovascular approach is a reliable and safe technique for management of cerebral mycotic aneurysms.
Insights
Endovascular treatment for cerebral mycotic aneurysms, often linked to rheumatic heart disease, proved safe and effective. This approach led to good neurological outcomes in most patients, demonstrating its reliability.
Area of Science:
- Neurology
- Vascular Surgery
- Infectious Diseases
Background:
- Cerebral mycotic aneurysms are rare but serious complications, frequently associated with infective endocarditis.
- Management options for these aneurysms have evolved, with endovascular techniques gaining prominence.
Purpose of the Study:
- To evaluate the safety and efficacy of endovascular management for cerebral mycotic aneurysms.
- To assess clinical outcomes and technical success rates of endovascular treatment in a cohort of patients.
Main Methods:
- Retrospective analysis of 13 patients with cerebral mycotic aneurysms treated between 2001 and 2007.
- Endovascular techniques included parent vessel occlusion for distal aneurysms and selective treatment for proximal ones.
Main Results:
- Technical success was achieved in all patients undergoing endovascular treatment.
- No rebleeding occurred post-embolization; however, two patients died due to increased mass effect from prior bleeds.
- Eleven patients had favorable outcomes, with eight achieving normal neurological status and three experiencing permanent disability related to the initial stroke.
Conclusions:
- Endovascular approach is a reliable and safe technique for managing cerebral mycotic aneurysms.
- The study highlights the potential for good long-term outcomes with timely endovascular intervention.
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