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Published on: August 11, 2015
Tissue reaction to new scalp clips
S Ratanalert1, S Chittrakarn, W Mittranun
1Department of Surgery, Prince of Songkla University, Songkhla, Thailand. sanguansin.r@psu.ac.th
British Journal of Neurosurgery
|January 29, 2008
Summary
Plastic hair clips showed minimal skin reaction in animal testing, comparable to standard Raney scalp clips. Clinical trials confirmed their safety for craniotomy procedures, suggesting a viable local alternative.
Area of Science:
- Biomaterials science
- Medical device development
- Dermatology
Background:
- Standard Raney scalp clips are widely used in surgical procedures.
- The need for accessible and safe alternatives to imported surgical instruments is recognized.
- Assessing the biocompatibility of novel materials for medical applications is crucial.
Purpose of the Study:
- To evaluate the skin compatibility of plastic hair clips.
- To compare the tissue reaction to plastic clips with standard Raney scalp clips.
- To determine the safety and efficacy of plastic clips in clinical surgical settings.
Main Methods:
- Animal testing was conducted to assess dermal reactions to plastic hair clips.
- Comparative analysis of skin reactions between plastic and Raney scalp clips.
- Clinical trials involving craniotomy procedures to evaluate clip safety.
Main Results:
- Animal testing revealed minimal skin reactions to plastic hair clips.
- The observed reactions were comparable to those caused by standard Raney scalp clips.
- Clinical trials demonstrated the safety of plastic clips during craniotomy procedures.
Conclusions:
- Plastic hair clips represent a potentially safe and effective local alternative to imported scalp clips.
- The findings support the use of these plastic clips in neurosurgical applications.
- Further research may explore broader clinical applications of these biocompatible clips.

