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Related Concept Videos

Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Kubler Ross's Stages of Dying01:21

Kubler Ross's Stages of Dying

Elisabeth Kübler-Ross significantly advanced psychology's understanding of the process of dying with her influential book, On Death and Dying (1969). She focused on studying terminally ill individuals and outlined five stages commonly experienced when coping with death: denial, anger, bargaining, depression, and acceptance.
In denial, individuals reject the reality of their condition, often thinking, "This isn't true; I feel fine," as a way to protect themselves from emotional distress. Anger...
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Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...

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Related Experiment Video

Updated: Jul 7, 2026

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

[Dying with dementia: what do we know about it?].

J T van der Steen1, M W Ribbe

  • 1Epidemioloog, wetenschappelijk medewerker, VU medisch centrum, EMGO Instituut, afdeling Verpleeghuisgeneeskunde en afdeling Sociale Geneeskunde. j.vandersteen@vumc.nl

Tijdschrift Voor Gerontologie En Geriatrie
|January 30, 2008
PubMed
Summary

Research on end-of-life care for dementia patients is growing, focusing on prognosis, decision-making, and family satisfaction. New prospective studies aim to improve care quality for those with dementia near death.

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Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum
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Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Published on: August 5, 2020

Related Experiment Videos

Last Updated: Jul 7, 2026

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum
04:36

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Published on: August 5, 2020

Area of Science:

  • Gerontology
  • Palliative Care
  • Dementia Research

Background:

  • End-of-life care for dementia patients is a growing concern due to increasing prevalence.
  • Research in this area, particularly in nursing homes, has been limited.
  • Existing studies cover prognosis, decision-making, treatment, patient suffering, and family satisfaction.

Purpose of the Study:

  • To review recent research on end-of-life care for patients with dementia.
  • To identify research gaps and future directions in this field.
  • To highlight ongoing prospective studies like CASCADE and DEOLD.

Main Methods:

  • Review of recent studies on end-of-life care in dementia.
  • Analysis of research domains: prognosis, decision-making, treatment, patient suffering, and family satisfaction.
  • Identification of qualitative and retrospective study designs.

Main Results:

  • Prognosis research focuses on mortality risk scores (6-12 months).
  • Decision-making is primarily studied qualitatively.
  • Treatment, patient suffering, and family satisfaction are covered by small, retrospective studies.

Conclusions:

  • Prospective studies like CASCADE and DEOLD are crucial for advancing research.
  • These studies will assess decision-making, family satisfaction, and patient suffering.
  • Findings will inform interventions to improve end-of-life care for dementia patients globally.