Antibacterial properties of novel poly(methyl methacrylate) nanofiber containing silver nanoparticles
1College of Engineering, Seoul National University, 56-1 Shinlim Kwanak, Seoul 151-742, Korea.
Abstract:
Poly(methyl methacrylate) (PMMA) nanofiber containing silver nanoparticles was synthesized by radical-mediated dispersion polymerization and applied to an antibacterial agent. UV-vis spectroscopic analysis indicated that the silver nanoparticles were continually released from the polymer nanofiber in aqueous solution. The antibacterial properties of silver/PMMA nanofiber against both Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria were evaluated using minimum inhibitory concentration (MIC), the modified Kirby-Bauer method, and a kinetic test. The MIC test demonstrated that the silver/PMMA nanofiber had enhanced antimicrobial efficacy compared to that of silver sulfadiazine and silver nitrate at the same silver concentration.
Related Concept Videos
Clinical Significance of Antibiotic Resistance
Microbial Corrosion


