Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Atomically dispersed cobalt on niobium oxide enables photothermal nitrogen fixation via nitrogen-hydrogen coupling.

Journal of colloid and interface science·2026
Same author

Glycosphingolipids regulate phosphatidylserine transport machinery that operates at ER-PM contact sites.

Nature communications·2026
Same author

Systems Biology of the Microsatellite Signature in 156 Genomes of the Viral Family Rhabdoviridae.

Current microbiology·2026
Same author

Prospects and challenges in intracellular delivery of therapeutic proteins.

Pharmacological reports : PR·2026
Same author

Engineering of genetically encoded programmable calcium channel inhibitory binders.

Nature communications·2026
Same author

Prenatal Aflatoxin B<sub>1</sub> Exposure: A Review of Pathogenesis and Impact on Fetal Skeletal Development and Ossification.

Toxins·2026

Related Experiment Video

Updated: Jul 7, 2026

A New Technique for Treating Low-risk Prostate Cancer&#8212;Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

Multidimensional approaches in dealing with prostate cancer.

Safdar Ali1, Sher Ali

  • 1Molecular Genetics Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi-110067, India.

Gene
|January 30, 2008
PubMed
Summary

Prostate cancer susceptibility genes are linked to multiple chromosomes, but inheritance patterns and specific genes remain debated. Current treatments target androgens and estrogens, with emerging therapies like vaccines and gene therapy.

More Related Videos

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization
07:34

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization

Published on: November 17, 2023

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Related Experiment Videos

Last Updated: Jul 7, 2026

A New Technique for Treating Low-risk Prostate Cancer&#8212;Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization
07:34

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization

Published on: November 17, 2023

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Area of Science:

  • Genetics and Oncology
  • Molecular Biology
  • Epidemiology

Background:

  • Prostate cancer is a major global health concern for males.
  • Genetic linkage studies suggest susceptibility genes on various chromosomes (1, 4, 8, 16, 17, 19, 20, X).
  • Discrepancies exist regarding inheritance modes and specific gene targets, with some studies reporting weak or no linkage.

Purpose of the Study:

  • To review the complexities of prostate cancer linkage analyses.
  • To discuss current and emerging treatment and management strategies for prostate cancer.

Main Methods:

  • Review of existing case-control, cohort, twin, and segregation analyses.
  • Analysis of literature on prostate cancer genetics, environmental factors, and treatment modalities.

Main Results:

  • Evidence supports genetic loci associated with prostate cancer susceptibility across multiple chromosomes.
  • Environmental factors, age, and diet also influence prostate cancer development.
  • Androgens and estrogens are key targets in current prostate cancer therapies.

Conclusions:

  • The genetic landscape of prostate cancer susceptibility is complex and requires further elucidation.
  • Established treatments include hormone therapy, radiation, and surgery.
  • Novel therapeutic avenues such as cancer vaccines and gene therapy show promise for future prostate cancer management.