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Updated: Jul 7, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

[Vertebral osteomyelitis due to Streptococcus agalactiae ST-17].

C Martinaud¹, T Gaillard, B Graffin

¹Laboratoire de biologie, Hôpital d'instruction des armées Sainte-Anne, Toulon. martinaud_christophe@yahoo.fr

Annales De Biologie Clinique

|January 30, 2008

Summary

Group B Streptococcus (GBS) vertebral osteomyelitis is rare in healthy adults. This case report details a successful treatment of GBS vertebral osteomyelitis in a 49-year-old man, highlighting GBS

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Area of Science:

Infectious Diseases
Microbiology
Clinical Medicine

Background:

Streptococcus agalactiae, or Group B Streptococcus (GBS), is primarily associated with neonatal and maternal infections.
Invasive GBS infections are increasingly reported in non-pregnant adults, particularly those with comorbidities like diabetes or cancer.
Vertebral osteomyelitis caused by GBS is an uncommon manifestation of invasive disease.

Observation:

A case of vertebral osteomyelitis caused by Streptococcus agalactiae in a 49-year-old male patient with no apparent risk factors is presented.
The infecting strain was identified as serotype III, sequence type ST-17, indicating specific virulence characteristics.
The patient received prolonged antibiotic therapy.

Findings:

The study confirms the potential for Streptococcus agalactiae to cause vertebral osteomyelitis in otherwise healthy adults.
Virulence factor assessment identified the strain as serotype III, ST-17.
The patient experienced a favorable outcome following extended antibiotic treatment.

Implications:

This case underscores the importance of considering GBS as a causative agent for vertebral osteomyelitis, even in the absence of typical risk factors.
Early diagnosis and appropriate management, including prolonged antibiotic therapy, are crucial for favorable outcomes.
Further research may elucidate the specific mechanisms and risk factors associated with GBS vertebral osteomyelitis in the adult population.