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Published on: April 22, 2017
[Expression of trophinin in human oocytes and preimplantation embryos]
Hua-Yun Wang1, Fu-Qi Xing, Shi-Ling Chen
1Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Objective:
To investigate the significance of trophinin expression in human oocytes and preimplantation embryos.
Methods:
The expression of trophinin in 9 human oocytes, 16 blastomeres and 12 blastocysts were detected by indirect immunofluorescence assay and observed under laser scanning confocal microscope.
Results:
Human oocytes, blastomeres and blastocysts were all positive for trophinin expression, and the positivity intensified significantly in the course of the embryonic development (P<0.05).
Conclusion:
Trophinin may play an important role in human embryo implantation by mediating homophilic adhesion between the embryo and the endometrium during the implantation window.
