Understanding the fibromyalgia syndrome
Srinivas G Rao1, Judith F Gendreau, Jay D Kranzler
1Cypress Bioscience, Inc., San Diego, CA, USA.
Abstract:
The fibromyalgia syndrome (FMS) is the most frequent cause of chronic, widespread pain. This review, which is targeted at the psychiatry and psychopharmacology communities, summarizes the state-of-the-art as it relates to both the pathophysiology and treatment of FMS. Toward this end, the anatomy and physiology of pain pathways are summarized, followed by a review of the altered biology of pain processing, neurotransmitter function, and neuroendocrine systems in FMS. The categories of current drugs employed to treat the disorder are detailed, along with a critical review of the literature supporting such use.
Related Concept Videos
Layers of Connective Tissue Proper
Irritable Bowel Syndrome
Ultrasound II: Endoscopic Ultrasound and FibroScan
Endoscopic Ultrasound (EUS):
Irritable Bowel Syndrome I: Introduction
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Nephrotic Syndrome I : Introduction
Myasthenia Gravis ll: Pathophysiology

