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Updated: Jul 7, 2026
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Live Imaging of Mitosis in the Developing Mouse Embryonic Cortex
Published on: June 4, 2014
Detection of mitotic figures and components of the mitotic machinery
1Princess Margaret Hospital and The Ontario Cancer Institute, Toronto, Ontario, Canada.
Current Protocols in Cell Biology
|January 30, 2008
Abstract:
Mitotic figures have provided important information on the mechanisms behind observed chromosomal aberrations. Variations in cell culturing and fixation methods enhance the visualization of mitotic figures. Furthermore, immunohistochemistry using a host of antibodies against protein structures involved in the cell cycle, as well as against those components involved in anchoring chromosomal structures, can reveal changes in chromosomal segregation.
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