Related Experiment Video
Updated: Jul 7, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
A child with pericardial effusion and cardiac tamponade due to previously unrecognized hypothyroidism
Srinath Sanda1, Ron S Newfield
1Division of Pediatric Endocrinology, University of Washington School of Medicine, Seattle, WA, USA. ssanda@benaroyaresearch.org
Insights
Undiagnosed hypothyroidism can lead to cardiac tamponade in children. Screening for hypothyroidism is crucial in pediatric patients with unexplained pericardial effusions to prevent this serious complication.
Area of Science:
- Pediatric Cardiology
- Endocrinology
- Internal Medicine
Background:
- Hypothyroidism, a condition of insufficient thyroid hormone production, can have diverse clinical manifestations.
- Pericardial effusion, the accumulation of fluid around the heart, can lead to cardiac tamponade, a life-threatening condition.
- Early recognition and management of hypothyroidism are vital to prevent severe cardiovascular complications.
Observation:
- A 12-year-old Hispanic female presented with early cardiac tamponade.
- The cardiac tamponade was attributed to pericardial effusion.
- The patient had previously unrecognized hypothyroidism as the underlying cause.
Findings:
- The case highlights a rare but serious presentation of hypothyroidism in a pediatric patient.
- Unexplained pericardial effusions in children may be a sign of underlying hypothyroidism.
- Cardiac tamponade can develop insidiously in the context of undiagnosed hypothyroidism.
Implications:
- Pediatric patients presenting with unexplained pericardial effusions warrant screening for hypothyroidism.
- Close monitoring for the development of cardiac tamponade is essential in pediatric patients diagnosed with hypothyroidism.
- This case underscores the importance of considering endocrine disorders in the differential diagnosis of pediatric cardiovascular emergencies.
Abstract:
We present a 12-year-old Hispanic girl without overt symptoms of hypothyroidism who presented with early cardiac tamponade from pericardial effusion due to previously unrecognized hypothyroidism. Pediatric patients with unexplained pericardial effusions should be screened for hypothyroidism and should be followed closely for the development of tamponade if found to have hypothyroidism.
More Related Videos
Related Concept Videos
Pericarditis IV: Nursing Management
Pericarditis II: Clinical Features and Diagnostic Tests
Pericarditis III: Medical Management
Cardiomyopathy II: Dilated Cardiomyopathy
Hyperthyroidism I: Introduction
Hyperthyroidism II: Pathophysiology

