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Related Concept Videos

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Cancer Prevention02:59

Cancer Prevention

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Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Related Experiment Video

Updated: Jul 7, 2026

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers
08:33

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers

Published on: January 5, 2024

A randomized trial of a representational intervention to decrease cancer pain (RIDcancerPain).

Sandra Ward1, Heidi Donovan2, Sigridur Gunnarsdottir3

  • 1School of Nursing, University of Wisconsin-Madison.

Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association
|January 31, 2008
PubMed
Summary
This summary is machine-generated.

The RIDcancerPain intervention effectively reduced cancer pain severity and attitudinal barriers in adults with metastatic cancer. Further research is needed to optimize this approach for greater efficacy.

Related Experiment Videos

Last Updated: Jul 7, 2026

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers
08:33

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers

Published on: January 5, 2024

Area of Science:

  • Psychology
  • Oncology
  • Pain Management

Background:

  • Cognitive representations of illness influence patient experiences.
  • Conceptual change theories inform interventions for chronic conditions.

Purpose of the Study:

  • To develop and test the efficacy of a representational intervention to decrease cancer pain (RIDcancerPain).
  • To evaluate the intervention's impact on pain severity, interference, and quality of life.

Main Methods:

  • A two-group randomized controlled trial (RCT) involving 176 adults with metastatic cancer pain.
  • Assessed outcome variables (pain severity, interference, quality of life) and mediating variables (attitudinal barriers, coping/medication use) at baseline, 1 month, and 2 months.
  • Compared the RIDcancerPain intervention group with a control group.

Main Results:

  • 150 participants completed the study.
  • The RIDcancerPain group showed significant decreases in attitudinal barriers to pain management compared to the control group.
  • The RIDcancerPain group also demonstrated greater reductions in pain severity over time, with barrier scores mediating this effect.

Conclusions:

  • The RIDcancerPain intervention demonstrated efficacy in reducing cancer pain severity and attitudinal barriers.
  • Further refinement of the RIDcancerPain intervention is warranted to enhance its overall effectiveness.