Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Three-Dimensional Microscopy in Microbiology

Three-Dimensional Microscopy in Microbiology

Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Motion correction of PET brain images through deconvolution: II. Practical implementation and algorithm optimization.

Physics in medicine and biology·2009

Same author

Motion correction of PET brain images through deconvolution: I. Theoretical development and analysis in software simulations.

Physics in medicine and biology·2009

Same author

Gated stress-only 99mTc myocardial perfusion SPECT imaging accurately assesses coronary artery disease.

Nuclear medicine communications·2003

Same author

Evaluation of left ventricular endocardial volumes and ejection fractions computed from gated perfusion SPECT with magnetic resonance imaging: comparison of two methods.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology·2001

Same author

Neural activity related to drug craving in cocaine addiction.

Archives of general psychiatry·2001

Same author

Linking sight and sound: fMRI evidence of primary auditory cortex activation during visual word recognition.

Brain and language·2001

Search research articles

Related Experiment Video

Updated: Jul 7, 2026

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Published on: November 14, 2019

Feature detection in 3-d medical images using shape information.

T L Faber, E M Stokely

IEEE Transactions on Medical Imaging

|January 1, 1987

Summary

This study evaluated three methods for locating the left ventricular apex in 3-D heart images. Quadratic surface methods proved superior, accurately identifying the apex regardless of image orientation.

Area of Science:

Cardiovascular Imaging
Medical Image Analysis
Computational Anatomy

Background:

Accurate identification of cardiac structures is crucial for diagnosis and treatment planning.
The left ventricular apex is a key landmark in cardiac imaging, but its precise localization can be challenging.
Existing methods may be sensitive to variations in patient positioning and image acquisition.

Purpose of the Study:

To investigate and compare the performance of three distinct methods for automated left ventricular apex identification.
To evaluate the robustness of these methods against variations in the orientation and positioning of cardiac blood pool images.
To determine the most reliable method for apex localization in 3-D gated blood pool tomograms.

Main Methods:

Developed and tested three algorithms for left ventricular apex detection in 3-D gated blood pool tomograms.

More Related Videos

Morphology-Based Distinction Between Healthy and Pathological Cells Utilizing Fourier Transforms and Self-Organizing Maps

Morphology-Based Distinction Between Healthy and Pathological Cells Utilizing Fourier Transforms and Self-Organizing Maps

Published on: October 28, 2018

Multicolor 3D Printing of Complex Intracranial Tumors in Neurosurgery

Multicolor 3D Printing of Complex Intracranial Tumors in Neurosurgery

Published on: January 11, 2020

Related Experiment Videos

Last Updated: Jul 7, 2026

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Published on: November 14, 2019

Morphology-Based Distinction Between Healthy and Pathological Cells Utilizing Fourier Transforms and Self-Organizing Maps

Morphology-Based Distinction Between Healthy and Pathological Cells Utilizing Fourier Transforms and Self-Organizing Maps

Published on: October 28, 2018

Multicolor 3D Printing of Complex Intracranial Tumors in Neurosurgery

Multicolor 3D Printing of Complex Intracranial Tumors in Neurosurgery

Published on: January 11, 2020

Method 1: Assumed fixed orientation and positioning of the cardiac blood pool.

Methods 2 & 3: Utilized quadratic surface shape models, invariant to position and orientation.

Main Results:

The orientation-dependent method (Method 1) performed well only with correctly oriented images.
Quadratic surface methods (Methods 2 & 3) demonstrated robust performance across various orientations.
The optimal quadratic surface method achieved high prediction accuracy for the apex coordinates (correlations of 0.97-0.99).

Conclusions:

Shape-based methods using quadratic surfaces offer a reliable approach for left ventricular apex identification in 3-D cardiac imaging.
These methods overcome the limitations of orientation-dependent techniques, improving clinical applicability.
The findings support the use of invariant shape models for robust anatomical landmark detection.