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Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

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Related Experiment Video

Updated: Jul 7, 2026

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

Published on: August 8, 2019

Fast point spread function computation from aperture functions in high-resolution positron emission tomography.

D Schmitt¹, B Karuta, C Carrier

¹Dept. of Electr. Eng., Sherbrooke Univ., Que.

IEEE Transactions on Medical Imaging

|January 1, 1988

Summary

This study presents a fast computation model for extracting point spread functions in high-resolution Positron Emission Tomography (PET). The method accurately assesses tomograph performance and aids in designing next-generation PET scanners.

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Last Updated: Jul 7, 2026

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

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Published on: August 8, 2019

Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET

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A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

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Published on: February 1, 2016

Area of Science:

Medical Imaging
Nuclear Medicine
Physics

Background:

Accurate point spread function (PSF) extraction is crucial for high-resolution Positron Emission Tomography (PET) imaging.
Existing methods may face challenges with computational complexity and reconstruction algorithm-induced errors.

Purpose of the Study:

To develop a fast and accurate method for extracting PSFs from detector aperture functions in high-resolution PET.
To enable precise assessment of intrinsic PET tomograph performance.
To facilitate the design of advanced, high-resolution PET systems.

Main Methods:

Developed a simplified computation model for PSF extraction under specific detector size conditions.
Assumed small detector sizes relative to ring dimensions for computational efficiency.
Validated the model's accuracy by minimizing reconstruction algorithm errors.

Main Results:

Achieved a fast and simple computation model for PSF extraction.
Demonstrated negligible errors introduced by the reconstruction algorithm.
Established a method to accurately relate imaging capabilities to detector characteristics.

Conclusions:

The developed method provides an accurate assessment of intrinsic PET tomograph performance.
It serves as a valuable tool for designing next-generation high-resolution PET scanners.
The approach effectively links imaging performance to the physical properties of the detection system.