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Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...

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Updated: Jul 7, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

[Obesity, personal and social problem].

Azra Biscević1, Mirza Biscević, Dragica Smrke

  • 1Medicinski fakultet Univerziteta u Sarajevu, BiH.

Medicinski Arhiv
|February 1, 2008
PubMed
Summary

Obesity significantly worsens knee function and increases pain, particularly in individuals with osteoarthritis. Addressing obesity is crucial for improving mobility and overall health outcomes.

Area of Science:

  • Orthopedics and Traumatology
  • Public Health
  • Rheumatology

Context:

  • Obesity is a major risk factor for numerous diseases, including cardiovascular conditions, diabetes, hypertension, certain cancers, and degenerative joint diseases.
  • It poses significant medical and social challenges, leading to both somatic and mental health issues, especially in females and younger individuals.
  • Some individuals resort to risky weight-loss methods or surgical procedures to manage body weight and alleviate psychological distress from perceived body deformities.

Purpose:

  • To quantify the negative impact of obesity on knee joint functionality.
  • To assess the relationship between obesity, knee function, pain, and disability in patients with osteoarthritis.
  • To highlight the importance of obesity prevention and treatment in managing knee-related health problems.

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A Method for Manipulating Blood Glucose and Measuring Resulting Changes in Cognitive Accessibility of Target Stimuli

Published on: August 12, 2016

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Last Updated: Jul 7, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
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Published on: May 30, 2025

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Methods for Presenting Real-world Objects Under Controlled Laboratory Conditions

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A Method for Manipulating Blood Glucose and Measuring Resulting Changes in Cognitive Accessibility of Target Stimuli
08:01

A Method for Manipulating Blood Glucose and Measuring Resulting Changes in Cognitive Accessibility of Target Stimuli

Published on: August 12, 2016

Summary:

  • A study analyzed 22 patients (5 male, 17 female) with severe knee osteoarthritis, averaging 63.6 years old and a Body Mass Index (BMI) of 31.1.
  • Knee functionality was evaluated using the Knee Society Knee Score (KSKS), with an average score of 118.1 out of 200.
  • Significant correlations were found between lower KSKS scores and older age, longer symptom duration, and increased pain levels, with obesity directly linked to heightened knee pain.

Impact:

  • Obesity significantly increases knee pain and reduces overall knee functionality, as evidenced by lower KSKS scores in obese patients.
  • Reduced functional abilities due to knee problems can lead to decreased physical activity, further exacerbating obesity and creating a negative cycle.
  • Effective prevention and treatment of obesity are essential to mitigate its impact on knee health, functional capacity, and the prevalence of common modern diseases.