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Updated: Jul 7, 2026
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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
[Gamma knife radiosurgery for temporal bone chondroblastoma: case report].
Shinichiro Mizumatsu1, Kyoji Sakai, Takushi Nishimura
1Department of Neurosurgery, Himeji Central Hospital, 2-36 Miyake, Shikama-ku, Himeji-city, Hyogo 672-8501, Japan.
No Shinkei Geka. Neurological Surgery
|February 1, 2008
Summary
Gamma Knife Radiosurgery (GKR) effectively controlled residual temporal bone chondroblastoma after surgery. This treatment reduced tumor size and resolved patient symptoms, offering a viable option for skull base tumors.
Area of Science:
- Neurosurgery
- Oncology
- Radiology
Background:
- Chondroblastoma is a rare bone tumor, occasionally affecting the skull base.
- Residual tumor after surgical excision of temporal bone chondroblastoma can lead to persistent symptoms.
Observation:
- A 52-year-old woman presented with residual temporal bone chondroblastoma, experiencing temporalgia and facial twitch.
- The expansile tumor (12.8 cm3) showed specific MRI characteristics: homogeneous hypo-intensity on T1/T2-weighted images with minimal contrast enhancement.
Findings:
- The patient received Gamma Knife Radiosurgery (GKR) with a marginal dose of 12 Gy and a maximum dose of 24 Gy.
- Following GKR, the tumor volume decreased to 6.4 cm3 within twenty months, and symptoms resolved completely one month post-treatment.
- The patient remained recurrence-free with no side effects for four years post-GKR.
Implications:
- GKR demonstrates potential efficacy in managing residual chondroblastoma of the skull base following surgical intervention.
- This case highlights GKR as a potential non-invasive therapeutic option for select skull base tumors, improving patient outcomes.