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Updated: Jul 7, 2026

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice
Published on: June 4, 2020
Recognition and its impairment regarding autobiographical memories in a patient with hippocampal amnesia
Mikio Hirano1, Ayumu Goukon, Toshihiko Kikuchi
1Faculty of Medical Science and Welfare, Tahoku Bunka Gakuen University, 6-45-1, Kunimi, Aobaku, Sendai 981-8551, Japan. hirano@hss.tbgu.ac.jp
Abstract:
Autobiographical memories of one case (Y.K.) were assessed before and after onset of hippocampal amnesia. He was a 56-yr.-old male patient who used to work in an office. The findings can be described as follows. First, Y.K.'s recognition performance regarding his premorbid and postmorbid personal semantics along with premorbid autobiographical incidents was significantly greater than chance, and recognition of premorbid autobiographical incidents was within chance. Given information before onset, a relationship was suspected between frontal lobe dysfunction and Y.K.'s autobiographical problem. The possibility that an amnesic patient could acquire semantic information after onset is discussed.
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