[The genetic substrate in cases with epileptogenic potential]

Among the manifestations with convulsive aspect, those apparently induced by fever in children are very important, especially if considered in perspective. This investigation was carried out in family backgrounds and it revealed that, in many such cases, the manifestations thought to be induced by fever had a family character, thus suggesting a possible genetic susceptibility. Most often, the maternal line was affected. A positive family history can be considered as a high risk factor and should not be ignored in all these children.