Related Experiment Video
Updated: Jul 7, 2026

Optical Screening of Novel Bacteria-specific Probes on Ex Vivo Human Lung Tissue by Confocal Laser Endomicroscopy
Published on: November 29, 2017
[Fluorescence endoscopy of the respiratory tract]
L Thiberville1, M Salaün, S Lachkar
1Clinique Pneumologique, Hôpital Charles-Nicolle, Centre Hospitalier et Universitaire de Rouen, Rouen cedex, France. luc.thiberville@univ-rouen.fr
Abstract:
Autofluorescence endoscopy has been used for more than 10 years in the diagnosis of early lung cancers and precancerous lesions of the bronchial tree. The technique has been extensively evaluated during the past decade and two recent large randomised studies have shown a 2 to 5 times increase in the detection of high grade pre-cancerous lesions compared with conventional white light endoscopy. This paper reviews the principal applications and results of the use of autofluorescence endoscopy in high risk individuals as well as innovative endoscopic approaches using the fluorescent properties of the respiratory tract.
Related Concept Videos
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due to...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Physical Assessment of the Respiratory Tract II: Inspection
Chest Configuration
The chest configuration can...
Endoscopic Procedures III: Video Capsule Endoscopy
Immunofluorescence Microscopy
The...
Total Internal Reflection Fluorescence Microscopy

