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Preliminary evidence for lipid peroxidation and changes in pro-oxidant status in brain tissue and blood in ethanol
I Mihăilescu1, M Mohora, V Dinu
1Department of Biochemistry, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania.
Abstract:
A single dose of ethanol to rats (6 g ethanol/kg body weight) resulted in an increase of lipid-peroxidation in brain, a decrease of anti oxidant enzyme activity in blood serum and alteration in red cell membrane permeability, possibly in an excess of oxygen derived free radicals and physical interaction with membranes.
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