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Updated: Jul 7, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
[Retinal central vein occlusion in remission of Crohn's disease: case report]
Iris de Souza Yamane1, Rafael da Silva Reis, Haroldo Vieira de Moraes
1Serviço de Oftalmologia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. irisyamane@gmail.com
Abstract:
Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis. Both diseases are characterized by chronic inflammation of the intestines. The advances in understanding the inflammatory process improved the treatment of inflammatory bowel disease. The systemic complications of inflammatory bowel disease involve several organs included the eyes. The incidence of eye complications in IBD is unknown, but according to the literature the incidence vary between 3.5% and 11.8%. The ophthalmic complications are usually of inflammatory origin. We report a case of a patient with Crohn's disease that developed central retinal vein occlusion and papillophlebitis without any other retinal vascular disease during remission. The aim of this paper is to reinforce the importance of complete ophthalmic examination perform as a routine in patients with inflammatory bowel disease.
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