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Neuroendocrine tumor in the breast
Hiroshi Ogawa1, Akiko Nishio, Hiroko Satake
1Department of Radiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8560, Japan. g050609d@mbox.nagoya-u.ac.jp
Radiation Medicine
|February 1, 2008
Summary
A woman with a history of ovarian carcinoid tumor developed a breast mass. Diagnosis revealed a primary breast neuroendocrine tumor and peritoneal carcinoid spread.
Area of Science:
- Oncology
- Endocrinology
- Radiology
Background:
- Neuroendocrine tumors (NETs) are rare neoplasms that can arise in various organs.
- Ovarian carcinoid tumors, a subtype of NETs, can present with diverse clinical manifestations.
- Metastasis of carcinoid tumors to the breast is exceptionally uncommon.
Observation:
- A 34-year-old woman with a known ovarian carcinoid tumor presented with a newly detected right breast mass.
- Imaging studies including mammography, ultrasonography, contrast-enhanced CT, and MRI revealed a suspicious breast lesion.
- A concurrent nodule in the pouch of Douglas was also identified.
Findings:
- Histopathological examination confirmed a primary neuroendocrine carcinoma of the breast (solid type).
- The nodule in the pouch of Douglas was diagnosed as peritoneal dissemination of the original ovarian carcinoid tumor.
- This case highlights a rare presentation of synchronous primary breast NET and metastatic disease.
Implications:
- This case underscores the importance of considering rare metastatic patterns in patients with a history of neuroendocrine tumors.
- It emphasizes the utility of advanced imaging modalities in the diagnosis and characterization of breast lesions in this context.
- Further research into the biological behavior and management of breast neuroendocrine tumors is warranted.
