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Published on: November 12, 2015
[Corneal melting after cross-linking and deep lamellar keratoplasty in a keratoconus patient]
P Eberwein1, C Auw-Hädrich, F Birnbaum
1Augenheilkunde, Universitätsklinik Freiburg. philipp.eberwein@uniklinik-freiburg.de
Abstract:
We present the case of a 45-year-old patient with severe atopic disease and keratoconus who suffered from corneal melting following cross-linking and deep anterior lamellar keratoplasty (DALK) due to subclinical infection with Herpes simplex virus (HSV). Penetrating keratoplasty and intensive antiviral and immunosuppressive medical treatment were necessary to control the infection. The case demonstrates the difficulties in the treatment of keratoconus in patients with severe atopic disease.
Insights
Severe atopic disease complicates keratoconus treatment. A patient experienced corneal melting after cross-linking and DALK due to a subclinical Herpes simplex virus infection, requiring further surgery and intensive medical care.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Infectious Diseases
Background:
- Keratoconus management can be challenging in patients with severe atopic disease.
- Corneal cross-linking and deep anterior lamellar keratoplasty (DALK) are common treatments for keratoconus.
Observation:
- A 45-year-old patient with severe atopic disease and keratoconus developed corneal melting post-operatively.
- The complication was attributed to a subclinical Herpes simplex virus (HSV) infection.
Findings:
- The patient required penetrating keratoplasty and intensive antiviral and immunosuppressive therapy.
- Successful management of the HSV infection was achieved through this aggressive treatment regimen.
Implications:
- This case highlights the increased risk of infectious complications in atopic patients undergoing keratoconus surgery.
- Careful screening for subclinical infections and individualized treatment strategies are crucial for managing keratoconus in patients with severe atopic disease.
