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Updated: Jul 7, 2026

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

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Published on: April 25, 2025

[Calcinosis conjunctivae in chronic blepharitis].

C Auw-Hädrich¹, T Reinhard

¹Universitäts-Augenklinik Freiburg. claudia.auw-haedrich@uniklinik-freiburg.de

Klinische Monatsblatter Fur Augenheilkunde

|February 1, 2008

Summary

This summary is machine-generated.

Phosphate-containing eye drops may promote corneal calcification and granulomas in chronic blepharitis patients. Switching to phosphate-free eye drops is recommended to prevent these complications.

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Area of Science:

Ophthalmology
Pathology

Background:

Chronic blepharitis is an inflammatory eyelid condition.
Conjunctival overgrowth can affect corneal health.

Observation:

A case study of a 53-year-old female with chronic blepharitis and corneal conjunctival overgrowth.
Histological examination revealed foreign body granulomas around calcification foci in the conjunctival overgrowth.

Findings:

Phosphate-containing eye drops may contribute to calcification and granuloma formation.
Chemokines such as Tumor Necrosis Factor-alpha (TNF-alpha), prevalent in blepharitis, might promote this process.

Implications:

Phosphate-free eye drops are recommended for patients with chronic blepharitis.
Avoiding phosphate-containing solutions may prevent corneal complications in susceptible individuals.