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Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

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Related Experiment Video

Updated: Jul 7, 2026

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Published on: April 7, 2017

[Endometrial adenosarcoma with rhabdomyoblastic differenciation].

Meriem Bel Haj Salah¹, Amina Mekni, Chelly Ines

¹Service d'Anatomie et de Cytologie Pathologique, obstetrique C. Maternité la Rabta.

La Tunisie Medicale

|February 2, 2008

Summary

This summary is machine-generated.

This case report details an uncommon endometrial adenosarcoma in a 59-year-old woman. The study discusses the clinicopathological characteristics and potential causes of this rare neoplasm.

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Last Updated: Jul 7, 2026

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Published on: April 7, 2017

Area of Science:

Gynecologic Oncology
Pathology

Background:

Mixed Mullerian Tumors (MMTs) are rare endometrial neoplasms with both mesenchymal and epithelial components.
Adenosarcoma, a subtype of MMT, features benign glandular elements and low-grade sarcomatous stroma.

Observation:

A 59-year-old woman presented with a three-month history of metrorrhagia and an enlarged uterus.
Imaging studies (ultrasound and CT) revealed a significant uterine mass without evidence of other tumors.

Findings:

Surgical management via hysterectomy with adnexectomy was performed.
Pathological examination confirmed an endometrial adenosarcoma, characterized by a mixture of mesenchymal and epithelial elements.

Implications:

This case highlights the importance of accurate pathological diagnosis for rare endometrial neoplasms.
Understanding the clinicopathological features of adenosarcoma is crucial for appropriate patient management and further research into its etiopathogeny.