Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Smallpox

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.

Accessory Structures of the Skin: Sebaceous Glands

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Staphylococcal Skin Infections

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

Development of Immunocompetence

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Serious Illness Communication Practices in Glioblastoma: An Institutional Perspective.

Journal of palliative medicine·2021

Same author

Hospice Enrollment, Future Hospitalization, and Future Costs Among Racially and Ethnically Diverse Patients Who Received Palliative Care Consultation.

The American journal of hospice & palliative care·2021

Same author

Posttraumatic stress disorder symptoms in patients with acute myeloid leukemia.

Cancer·2021

Same author

Improved Serious Illness Communication May Help Mitigate Racial Disparities in Care Among Black Americans with COVID-19.

Journal of general internal medicine·2021

Same author

Serious Illness Conversations With Outpatient Oncology Clinicians: Understanding the Patient Experience.

JCO oncology practice·2020

Same author

Patient Risk Factor Profiles Associated With the Timing of Goals-of-Care Consultation Before Death: A Classification and Regression Tree Analysis.

The American journal of hospice & palliative care·2020

Search research articles

Related Experiment Video

Updated: Jul 7, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

Newborn skin: Part I. Common rashes.

Nina R O'Connor¹, Maura R McLaughlin, Peter Ham

¹Chestnut Hill Hospital Family Practice Residency Program, Philadelphia, Pennsylvania, USA.

American Family Physician

|February 2, 2008

Summary

Newborn rashes are common, with most being harmless. This guide helps distinguish benign conditions like erythema toxicum neonatorum from infections, offering management strategies for common infant skin issues.

Area of Science:

Neonatal Dermatology
Pediatric Skin Conditions

Background:

Neonatal rashes are a frequent cause of parental anxiety.
While many are benign, some require medical evaluation.
Understanding common neonatal dermatoses is crucial for appropriate management.

Purpose of the Study:

To provide a clinical overview of common newborn rashes.
To differentiate benign neonatal rashes from those indicating infection.
To guide management strategies for various infant skin conditions.

Main Methods:

Clinical diagnosis based on characteristic rash appearances.
Identification of key features for differentiating common neonatal rashes.
Review of management approaches for benign and infectious causes.

More Related Videos

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Related Experiment Videos

Last Updated: Jul 7, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Main Results:

Erythema toxicum neonatorum, acne neonatorum, and transient neonatal pustular melanosis are clinically diagnosable vesiculopustular rashes.
Milia and miliaria are linked to immature skin structures.
Seborrheic dermatitis is common and distinct from atopic dermatitis.

Conclusions:

Most newborn rashes are transient and benign, requiring reassurance.
Clinical differentiation is key for conditions like erythema toxicum neonatorum.
Infections and persistent cases necessitate further evaluation and treatment.