Related Experiment Video
Updated: Jul 7, 2026

06:27
Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Newborn skin: Part II. Birthmarks.
Maura R McLaughlin1, Nina R O'Connor, Peter Ham
1University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA.
American Family Physician
|February 2, 2008
Summary
Most newborn birthmarks are benign and require no treatment, but some, like large congenital melanocytic nevi and spinal dysraphism markers, need medical evaluation. Family physicians should guide parents on birthmark management and cosmetic options.
Area of Science:
- Pediatrics
- Dermatology
- Genetics
Background:
- Birthmarks are common in newborns, causing parental anxiety.
- Current management guidelines often rely on expert opinion rather than robust evidence.
- Distinguishing benign from potentially serious birthmarks is crucial for appropriate care.
Purpose of the Study:
- To provide an overview of common newborn birthmarks.
- To outline evidence-based management and treatment strategies for various birthmarks.
- To highlight concerning signs requiring further investigation.
Main Methods:
- Review of existing literature and clinical guidelines.
- Categorization of birthmarks based on clinical presentation and risk.
- Emphasis on diagnostic evaluation and treatment options.
Main Results:
- Most birthmarks, including dermal melanosis, hemangioma of infancy, port-wine stains, and nevus simplex, are benign and may not need treatment.
- Large congenital melanocytic nevi warrant evaluation for removal.
- Specific skin markers indicate potential spinal dysraphism, necessitating imaging (MRI/ultrasonography).
Conclusions:
- Family physicians need to be knowledgeable about birthmark diagnosis and management.
- Early identification of high-risk birthmarks is essential for timely intervention.
- Cosmetic laser treatments offer effective options for benign vascular and pigmented lesions.
Related Concept Videos
Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Healing II: Complications
Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Changes in Skin Color: Clinical Perspectives
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Pigmentation
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Papillary Dermis
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...

