Related Experiment Video
Updated: Jul 7, 2026
07:02
Minimally Invasive Embryo Transfer and Embryo Vitrification at the Optimal Embryo Stage in Rabbit Model
Published on: May 16, 2019
[Elective single embryo transfer (eSET)--the way to decrease the risk for multiple pregnancy].
1Centrum asistované reprodukce SANUS, Hradec Králové. rstreda@seznam.cz
Ceska Gynekologie
|February 2, 2008
Summary
Single embryo transfer (SET) significantly reduces multiple births and associated risks. This strategy offers live birth rates comparable to double embryo transfer, especially for younger women in early IVF cycles.
Area of Science:
- Reproductive Medicine
- In Vitro Fertilization (IVF)
- Obstetrics
Context:
- High multiple birth rates (25%) following double embryo transfer (DET) in IVF increase maternal and infant morbidity.
- Randomized controlled trials (RCTs) provide evidence for alternative strategies.
Purpose:
- To review trials and discuss single embryo transfer (SET) as a method to reduce multiple pregnancy rates.
- To evaluate the efficacy of SET in achieving live birth rates while minimizing twin risks.
Summary:
- SET offers a live birth rate of approximately 35% with a minimized risk of twins.
- Recommended for young women (≤36 years) in their first or second IVF cycle with sufficient good-quality embryos.
- A strategy combining fresh and frozen-thawed SET achieves live birth rates comparable to DET.
Impact:
- Reduces the incidence of multiple pregnancies in assisted reproductive technology.
- Lowers the morbidity associated with twin pregnancies for mothers and newborns.
- Provides a safer and effective alternative to DET in IVF.
Related Concept Videos
01:24In Vitro Fertilization
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
01:57Meiosis II
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each containing...